Ventures Portfolio

Cardionomic

Cardionomic

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About the Company: Cardionomic is developing a neuromodulation device for the management of acute decompensated heart failure (ADHF) by improving cardiac output via improved contractility. The inpatient cost of ADHF care is extremely high – accounting for 60% of total heart failure expenditures.

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Cashel Neural

Cashel Neural

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About the Company: Cashel Neural is developing novel small molecules that promote remyelination for the treatment of Multiple Sclerosis.

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Cell X Technologies

Cell X Technologies

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About the Company: Cell X Technologies develops and commercializes precision robotic technologies that span the entire cell manufacturing process.

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Centerline Biomedical

Centerline Biomedical

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About the Company: Centerline’s Intra-Operative Positioning System (IOPS) is a platform technology that enhances visualization and navigation across a range of endovascular procedures, while reducing exposure to harmful radiation for patients and physicians. 
 

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Cleveland Diagnostics

Cleveland Diagnostics

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About the Company: Cleveland Diagnostics is a biotechnology company with proprietary first-in-class technology and reagents to enable development of high efficacy and affordable tests, focused on early detection and diagnostics of cancer and neurodegenerative diseases.

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Cleveland HeartLab

Cleveland HeartLab

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About the Company: Cleveland HeartLab developed innovative, scientifically proven, and medically relevant biomarkers used in the management and prevention of cardiovascular disease. (Acquired by Quest Diagnostics, 2017) 
 

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Custom Orthopaedic Solutions

Custom Orthopaedic Solutions

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About the Company: Custom Orthopaedic Solutions developed preoperative planning software and produced patient specific bone models to improve the accuracy and outcomes of orthopaedic surgeries. (Acquired by Arthrex, 2018)
 

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Enspire DBS Therapy

Enspire DBS Therapy

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About the Company: Enspire DBS Therapy aims to revitalize stroke recovery using deep brain stimulation alongside physical rehabilitation to restore motor function for stroke survivors living with disability.

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Explorys

Explorys

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About the Company: Explorys provided a healthcare cloud-computing platform for enterprise performance management to integrated healthcare systems to identify patterns in diseases, treatments, and outcomes. (Acquired by IBM, 2015)
 

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Family Care Path

Family Care Path

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About the Company: Family Care Path collects and analyzes family history and other phenotypic information to improve population health management and clinical decision support across a range of hereditary conditions.  The Company has also developed a CRM-based tool to help better navigate cancer patients along their journey from initial diagnosis through treatment.
 

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FlexLife Health

FlexLife Health

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About the Company: FlexLife Health, in collaboration with NASA, developed a remote patient monitoring technology for the care of chronically managed patients. (Acquired by LifeWatch AG, 2015)
 

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ImageIQ

ImageIQ

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About the Company: ImageIQ was an innovative contract research organization that specialized in advanced medical image acquisition, analysis, and visualization for use in medical device and pharmaceutical clinical trials. (Acquired by ERT, 2017)

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Juventas Therapeutics

Juventas Therapeutics

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About the Company: Juventas Therapeutics is a clinical-stage biotechnology company developing a pipeline of regenerative therapies that activate natural processes to repair the body in order to treat life–threatening diseases.

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Mitria Medical

Mitria Medical

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About the Company: Mitria Medical is developing a minimally invasive transcatheter mitral valve repair implant.

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NaviGate Cardiac Structures

NaviGate Cardiac Structures

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About the Company: NaviGate Cardiac Structures Inc. (NCSI) is developing transcatheter tricuspid valve replacement solution for the treatment of tricuspid regurgitation.

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NeuroTherapia

NeuroTherapia

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About the Company: NeuroTherapia is a clinical stage biotechnology company developing novel therapies that decrease the neuroinflammation associated with diseases such as neuropathic pain and Alzheimer’s disease.
 

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Perfusion Solutions

Perfusion Solutions

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About the Company: Perfusion Solutions is developing a minimally-invasive implantable ultra-small heart pump technology for acute and chronic heart failure.

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VisionAir Solutions

VisionAir Solutions

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About the Company: VisionAir Solutions designs and manufactures 3D patient-specific silicon airway stents, eliminating the need for onsite modification.

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Xealth

Xealth

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About the Company: Xealth is a digital health prescribing platform that enables clinicians to easily integrate, prescribe, and monitor digital health tools for patients from their EHR workflows.

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XII Medical

XII Medical

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About the Company: XII Medical is developing a minimally-invasive outpatient technology for the treatment of obstructive sleep apnea (OSA).

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Zenha Therapeutics

Zenha Therapeutics

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About the Company: Zehna Therapeutics is developing a novel small molecule targeting the gut microbiome to treat chronic disease.

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